Is orotic acid safe

The european food safety authority (efsa) has found 10 forms of orotic acid, or vitamin b13, cannot be deemed safe, after conducting a review.The test measures the levels of orotic acid in the urine.It is also required for the conversion of vitamin d (also known as the sunshine vitamin) into its active form.1.3 details of the supplier of the safety data sheet company:Orotic acid is also elevated in the transport defects of dibasic amino acids (lysinuric protein intolerance and hyperornithinemia, hyperammonemia, and homocitrullinuria [hhh] syndrome) and is greatly elevated in patients with hereditary orotic aciduria (uridine monophosphate synthase [umps] deficiency).

Carboxylic acids, such as orotic acid, donate hydrogen ions if a base is present to accept them.The recommended dietary allowance for orotic acid powderranges from 500 to 1,000 milligrams daily for adults.It was originally introduced as a vitamin, called vitamin b13, but essentiality has not been demonstrated.As an athletic supplement, it may improve endurance, promote muscle growth, and speed up workout recovery.The safety of the nutrient cations themselves, in terms of amounts that may be consumed, is outside the remit of this panel.

This can be collected randomly or at a scheduled time.I'm not sure how that works exactly.As a dietary supplement, take 500 mg (1/4 tsp) to 1000 mg (1/2 tsp) daily, or as directed by a physician.